CBG is a cannabinoid that comes from cannabis plants. It is often called the mother of all cannabinoids. It is because other cannabinoids come from cannabigerolic Acid (CBGA), which is an acidic form CBG.
Other cannabinoids that are more commonly obtained from cannabis plants include Cannabidiol, (CBD), and Tetrahydrocannabinol.
CBG can be found in lower amounts than other cannabinoids within cannabis plants. CBG is found in smaller amounts than other cannabinoids in cannabis plants. 1
Consumer products made from cannabinoid are rare and expensive. CBG is gaining popularity due to the numerous benefits it offers.
How CBG is Made
CBG is obtained from young cannabis plants. These plants have higher levels of CBG than mature plants.
White CBG and Super Glue CBG are some strains that have higher CBG than others. These strains are cultivated specifically to produce more CBG Oil.
CBD, and THC begin as CBGA. This is an acidic form CBG. Younger cannabis plants have higher levels of CBG.
CBG concentrations in fully developed plants with high levels of CBD and THC will be very low. Because most of the CBG was converted to CBD and HHC during plant development, this is possible.
Cannabis growers are trying to increase the production of CBG because it is difficult to obtain CBG.
How CBG works
The body's endocannabinoid system processes CBG. The body's endocannabinoid systems is composed of molecules and receptors that help maintain a healthy body regardless of external influences.
CBG mimics the natural compounds that our bodies make, such as endocannabinoids.
Cannabinoid receptors in the body
There are two types of cannabinoid-receptors in the body: CB1 and CB2. CB1 receptors can be found in the brain and nervous system, and CB2 receptors can be found in the immune system and in other parts of the body.
CBG acts by binding to both receptors. It is thought to enhance the function of anandamide (a neurotransmitter which plays a role in pleasure and motivation, appetite regulation, sleep and pain relief), where it can be found. CBG does not have psychotropic effects like THC.
CBG has potential benefits
CBG, like CBD, has been used to treat pain without the intoxicating effects of cannabinoids such as THC.
Research has shown that CBG can also have therapeutic benefits. Human studies on CBG are limited, so more research is required.
A few promising animal studies have shown that CBG may be able to treat some medical conditions.
Inflammatory Bowel Disease (IBD).
Chronic inflammation of the bowel causes inflammation. It is incurable and affects millions.
In 2013, an experimental animal study showed that CBG had beneficial effects on inflammatory bowel diseases. 2
Researchers infected mice with inflammation similar to IBD and administered CBG. CBG was shown to decrease inflammation and the production nitric oxygen. It also decreased the formation of reactive oxygen substances (ROSs) in the intestines. CBG should be considered as a clinical experiment in IBD patients.
Glaucoma
Researchers discovered that CBG can be used to treat glaucoma in animals.
CBG was administered to cats suffering from glaucoma by a team of researchers. They noticed a decrease in eye pressure as well as an increase in aqueous humor output. This fluid is produced by the eye and helps maintain eye pressure. 3
Huntington's Disease
Huntington’s disease is a condition that causes the brain to lose nerve cells. Researchers examined the neuroprotective potential of CBG and other cannabisoids in mice with Huntington's disease. CBG was found to be neuroprotective, protecting brain nerve cells from injury. CBG also helped to improve motor skills and protect striatal neurons from 3-nitropropionic acid poisoning. 4
Antibacterial Properties
A 2020 study on the antibiotic potential of cannabis found that CBG has antibacterial properties, especially against methicillin-resistant strains of Staphylococcus aureus (MRSA), the drug-resistant bacteria that causes staph infections.5
Fighting Cancer Cells
CBG was found to be effective in blocking cancer cell growth receptors in rats with colon cancer. It also inhibited the growth of colorectal carcinoma cells in a 2014 study. CBG should be considered for the prevention and treatment of colon cancer. 6
How to Use CBG
Oil is the most commonly available form of CBG, but it's rare and costly.
Broad-spectrum CBD oil contains almost all of the cannabinoids found in cannabis. This includes CBG, but not THC. The entourage effect is a phenomenon that increases the effectiveness of cannabinoids when they are combined.
Side effects of CBG
Respondents to the first survey on patients who used Best CBG Oil UK to treat insomnia, chronic pain, depression and anxiety reported side effects such as dry mouth, dry eyes, dry stomach, dry lips, dry skin, dry eyes, and hunger. CBG proved to be more effective than traditional medications 7, which can have serious side effects and addiction.
Although research on CBG's potential side effects and drug interactions risks is growing, not enough data has been collected to be able to determine CBG’s drug interactions risks and drug side effects.
CBG vs. CBD
CBG shares many similarities to CBD:
- Both are dependent on the endocannabinoid systems.
- They are not psychoactive. This means they don't give you a high.
- They can counteract THC’s psychotropic effects.
The biggest difference between CBD and CBG lies in the fact that most marijuana plants have only 1% of CBG, but as high as 25% CBD.
CBG interacts with the endocannabinoid systems differently than CBD. CBG can bind directly to both CB1-CB2 receptors, which could make it more efficient to deliver its benefits to the system.
CBG Scarcity
CBG is more difficult to make than THC, CBD and other cannabinoids. CBG shares many similarities to CBD so manufacturers prefer to produce CBD. CBG products are therefore very expensive. CBG's potential advantages aside, researchers are exploring ways to increase CBG's availability and reduce production problems.